Literature DB >> 10527271

Management of the neck in cancer of the larynx.

E N Myers1, J F Fagan.   

Abstract

In the Department of Otolaryngology at the University of Pittsburgh School of Medicine, cancer of the larynx is usually treated by primary surgery. Radiotherapy is used as adjuvant treatment in certain patients who have cancer that has adverse histologic features such as perineural, vascular, and/or cartilage invasion. With this approach, patients rarely develop local recurrence. Patient survival is therefore unlikely to be improved by changes to the management of the primary tumor. Survival may, however, be improved by reducing the incidence of recurrence in the neck, as well as distant. Hence, we have adopted an aggressive surgical approach to the cN+ as well as the N0 neck. The theoretical basis for this aggressive surgical approach to the neck will be considered under the following headings: staging, regional control, distant metastasis, survival, choice of neck dissection, and the pathologically positive elective neck dissection.

Entities:  

Mesh:

Year:  1999        PMID: 10527271     DOI: 10.1177/000348949910800902

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  4 in total

1.  Role of perineural invasion as a prognostic factor in laryngeal cancer.

Authors:  Massimo Mesolella; Brigida Iorio; Gabriella Misso; Amalia Luce; Mariano Cimmino; Maurizio Iengo; Mario Landi; Pasquale Sperlongano; Michele Caraglia; Filippo Ricciardiello
Journal:  Oncol Lett       Date:  2016-02-24       Impact factor: 2.967

2.  Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma.

Authors:  Wei Wang; Peng Lin; Chunrong Han; Wenjuan Cai; Xiulan Zhao; Baocun Sun
Journal:  J Exp Clin Cancer Res       Date:  2010-06-02

Review 3.  Advanced larynx cancer.

Authors:  Scott E Strome; Eric C Weinman
Journal:  Curr Treat Options Oncol       Date:  2002-02

4.  Neck dissection in squamous cell carcinoma of the larynx: indication of elective contralateral neck dissection.

Authors:  Ali Amar; Helma Maria Chedid; Sergio Altino Franzi; Abrão Rapoport
Journal:  Braz J Otorhinolaryngol       Date:  2012-04
  4 in total

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