Literature DB >> 1052542

Mechanism of the mutagenic action of hydroxylamine. IX. The UV-induced cleavage of the N-O bond in N4-hydroxy-and N4-methoxycytidine and N6-methoxyadenosine.

N A Simukova, D Y Yakovlev, E I Budowsky.   

Abstract

The principal UV-induced (lambda = 2546nm) reaction of N4-hydroxy- and N4methoxycytidines and N6-methoxyadenosine in neutral aqueous solutions is cleavage of the exocyclic N-O bond with the respective formation of cytidine and adenosine. Quantum yields are 2.8x10(-3) and 2.2x10(-3) M/E for the first two compounds and 9.1x10(-3) M/E for N6-methoxyadenosine.

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Year:  1975        PMID: 1052542      PMCID: PMC343594          DOI: 10.1093/nar/2.12.2269

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  8 in total

Review 1.  The mechanism of the mutagenic action of hydroxylamines.

Authors:  E I Budowsky
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1976

Review 2.  The lesions produced by ultraviolet light in DNA containing 5-bromouracil.

Authors:  F Hutchinson
Journal:  Q Rev Biophys       Date:  1973-05       Impact factor: 5.318

3.  The reaction of hydroxylamine with 4-thiouridine.

Authors:  S Iida; K C Chung; H Hayatsu
Journal:  Biochim Biophys Acta       Date:  1973-05-10

4.  The tautomeric state of N(4)-hydroxy- and of N(4)-amino-cytosine derivatives.

Authors:  D M Brown; M J Hewlins; P Schell
Journal:  J Chem Soc Perkin 1       Date:  1968

5.  Rate constants for the dehydration of single and double hydrates of cytidylyl (3'-5')--cytidine.

Authors:  P V Hariharan; H E Johns
Journal:  Photochem Photobiol       Date:  1968-03       Impact factor: 3.421

6.  Properties of thymine dimers.

Authors:  M A Herbert; J C LeBlanc; D Weinblum; H E Johns
Journal:  Photochem Photobiol       Date:  1969-01       Impact factor: 3.421

7.  Phototransformation of 4-thiouridine in Escherichia coli valine transfer ribonucleic acid to uridine, cytidine, and N 4 -methylcytidine.

Authors:  M G Pleiss; P A Cerutti
Journal:  Biochemistry       Date:  1971-08-03       Impact factor: 3.162

8.  Photochemical transformation of N1-methoxyadenine and N1-methoxy-9-methyladenine.

Authors:  Z Kazimierczuk; J Giziewicz; D Shugar
Journal:  Acta Biochim Pol       Date:  1973       Impact factor: 2.149

  8 in total

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