Literature DB >> 10523804

Chimeric monoclonal anti-CD20 antibody (rituximab)--an effective treatment for a patient with relapsing hairy cell leukaemia.

H Hagberg1.   

Abstract

A case story is presented, describing a 46 y old man, with a relapsing hairy cell leukaemia. After treatment with monoclonal anti CD-20 antibodies (rituximab) 375mg/week, four times, a complete remission was obtained which has lasted >9 months. The rituximab treatment produced a better remission than earlier treatments with alpha-interferon and chlorodeoxyadenosine. In addition, in contrast to other treatments, no initial worsening of the pancytopenia was observed.

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Year:  1999        PMID: 10523804     DOI: 10.1007/bf02906136

Source DB:  PubMed          Journal:  Med Oncol        ISSN: 1357-0560            Impact factor:   3.064


  2 in total

1.  Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the Group C protocol mechanism of the National Cancer Institute: a report of 979 patients.

Authors:  B D Cheson; J M Sorensen; D A Vena; M J Montello; J A Barrett; E Damasio; M Tallman; L Annino; J Connors; B Coiffier; F Lauria
Journal:  J Clin Oncol       Date:  1998-09       Impact factor: 44.544

2.  Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

Authors:  P McLaughlin; A J Grillo-López; B K Link; R Levy; M S Czuczman; M E Williams; M R Heyman; I Bence-Bruckler; C A White; F Cabanillas; V Jain; A D Ho; J Lister; K Wey; D Shen; B K Dallaire
Journal:  J Clin Oncol       Date:  1998-08       Impact factor: 44.544

  2 in total
  3 in total

Review 1.  Antibody-based therapy of leukaemia.

Authors:  John C Morris; Thomas A Waldmann
Journal:  Expert Rev Mol Med       Date:  2009-09-30       Impact factor: 5.600

Review 2.  Hairy cell leukemia-new genes, new targets.

Authors:  Robert J Kreitman
Journal:  Curr Hematol Malig Rep       Date:  2013-09       Impact factor: 3.952

Review 3.  Hairy cell leukemia.

Authors:  L Savoie; J B Johnston
Journal:  Curr Treat Options Oncol       Date:  2001-06
  3 in total

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