Literature DB >> 10522904

Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosis.

M Fernandez-Arquero1, R Arroyo, A Rubio, C Martin, P Vigil, L Conejero, M A Figueredo, E G de la Concha.   

Abstract

The associations of three promoter polymorphisms in the tumor necrosis factor (TNFA) gene have been studied in 238 patients and 324 control subjects. A significant correlation was found between MS susceptibility and the TNFA-376 polymorphism. This association was independent of the human leukocyte antigen (HLA) class II association and the combined inheritance of HLA-DRB1*1501 and the TNFA-376A allele more than additively increased susceptibility to MS.

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Year:  1999        PMID： 10522904     DOI： 10.1212/wnl.53.6.1361

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  13 in total

1.  Patterns of nucleotide sequence variation in ICAM1 and TNF genes in twelve ethnic groups of India: roles of demographic history and natural selection.

Authors:  Sanghamitra Sengupta; Shabana Farheen; Neelanjana Mukherjee; Partha P Majumder
Journal:  J Genet       Date:  2007-12       Impact factor: 1.166

2.  Optic Neuritis Associated or Not with TNF Antagonists in Patients with Inflammatory Bowel Disease.

Authors:  Benjamin Alexandre; Yves Vandermeeren; Olivier Dewit; Tom Moreels; Nanne de Boer; Anjan Dhar; Chris Ziady; Ariella Bar-Gil Shitrit; Flavio Steinwurz; Njegica Jojic; Giuseppe Costantino; Benoit Bihin; Jean-François Rahier; Konstantinos H Katsanos
Journal:  J Crohns Colitis       Date:  2016-01-12       Impact factor: 9.071

Review 3.  Genetics of inflammatory bowel disease: the role of the HLA complex.

Authors:  Tariq Ahmad; Sara-E Marshall; Derek Jewell
Journal:  World J Gastroenterol       Date:  2006-06-21       Impact factor: 5.742

4.  ISSLS PRIZE IN CLINICAL SCIENCE 2018: longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode-the good, the bad, and the ugly.

Authors:  David M Klyne; Mary F Barbe; Wolbert van den Hoorn; Paul W Hodges
Journal:  Eur Spine J       Date:  2018-02-19       Impact factor: 3.134

5.  The polymorphisms of the TNF-α gene in multiple sclerosis?--a meta-analysis.

Authors:  Lidan Xu; Weiguang Yuan; Haiming Sun; Xuelong Zhang; Xueyuan Jia; Chao Shen; Yanling Zhao; Donglin Sun; Yang Yu; Yan Jin; Songbin Fu
Journal:  Mol Biol Rep       Date:  2010-12-07       Impact factor: 2.316

6.  Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis.

Authors:  Justin P Rubio; Melanie Bahlo; Helmut Butzkueven; Ingrid A F van Der Mei; Michèle M Sale; Joanne L Dickinson; Patricia Groom; Laura J Johnson; Rex D Simmons; Brian Tait; Mike Varney; Bruce Taylor; Terence Dwyer; Robert Williamson; Nicholas M Gough; Trevor J Kilpatrick; Terence P Speed; Simon J Foote
Journal:  Am J Hum Genet       Date:  2002-03-29       Impact factor: 11.025

7.  Tumor necrosis factor alpha gene -376 polymorphism and susceptibility to multiple sclerosis: an Egyptian study.

Authors:  Mona Abd el Fattah Nada; Dalia Ahmed Labib
Journal:  J Neuroimmune Pharmacol       Date:  2010-05-25       Impact factor: 4.147

8.  DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands.

Authors:  Emilio G de la Concha; María L Cavanillas; M Carmen Cénit; Elena Urcelay; Rafael Arroyo; Óscar Fernández; José C Álvarez-Cermeño; Laura Leyva; Luisa M Villar; Concepción Núñez
Journal:  PLoS One       Date:  2012-02-17       Impact factor: 3.240

9.  HLA and celiac disease susceptibility: new genetic factors bring open questions about the HLA influence and gene-dosage effects.

Authors:  Luz María Medrano; Bárbara Dema; Arturo López-Larios; Carlos Maluenda; Andrés Bodas; Natalia López-Palacios; M Ángeles Figueredo; Miguel Fernández-Arquero; Concepción Núñez
Journal:  PLoS One       Date:  2012-10-31       Impact factor: 3.240

Review 10.  Defining the role of the MHC in autoimmunity: a review and pooled analysis.

Authors:  Michelle M A Fernando; Christine R Stevens; Emily C Walsh; Philip L De Jager; Philippe Goyette; Robert M Plenge; Timothy J Vyse; John D Rioux
Journal:  PLoS Genet       Date:  2008-04-25       Impact factor: 5.917
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