| Literature DB >> 10522694 |
K Wiśniewski1, J Trojnar, P Riviere, R Haigh, C Yea, D Ashworth, P Melin, A Nilsson.
Abstract
The synthesis of a new class of oxytocin antagonists, with significantly modified C-terminal part, is described. The chemistry of the Mitsunobu reaction was applied to obtain the key derivatives. In spite of the extensive modifications of previously described compound F792, the peptides retain biological activity as oxytocin antagonists.Entities:
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Year: 1999 PMID： 10522694 DOI： 10.1016/s0960-894x(99)00478-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823