| Literature DB >> 10522690 |
O Llorens1, J J Perez, A Palomer, D Mauleon.
Abstract
Molecular modeling studies performed on the two cyclooxygenase (COX) isozymes suggest that the cavity at the mouth of the active site on the membrane domain that may act as an actual binding site of COX ligands. Actual docking of different inhibitors at this site provides a structural basis to explain the dynamics of COX inhibition.Mesh：
Substances：
Year: 1999 PMID： 10522690 DOI： 10.1016/s0960-894x(99)00481-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823