| Literature DB >> 10520302 |
F Sztaricskai1, I E Takács, F Pusztai, G Szabó, I Csípõ.
Abstract
Starting from methyl 5-nitrosalicylate (20) the N- and O-beta-glucopyranosyl derivatives (24, 28) of 5-aminosalicylic acid were prepared. The LD50 values of these compounds were determined on mice, and the inhibitory effect of 24 (0.83 mmol/kg) and 28 (1.2 mmol/kg) on gastric ulcer on rats, induced by indomethacin was investigated.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10520302 DOI： 10.1002/(sici)1521-4184(19999)332:9<321::aid-ardp321>3.0.co;2-a
Source DB: PubMed Journal: Arch Pharm (Weinheim) ISSN： 0365-6233 Impact factor: 3.751