Literature DB >> 10516466

DNA vaccines.

J Encke1, J zu Putlitz, J R Wands.   

Abstract

Chronic infections with hepatitis B (HBV) and hepatitis C (HCV) virus are worldwide problems often leading to the development of chronic liver disease and hepatocellular carcinoma. Genetic immunizations with DNA encoding for structural and nonstructural proteins of HCV and HBV in experimental mice generate a broad base CD4+ and CD8+ cellular immune response which may be required for viral clearance from the host. DNA based immunization is a promising antiviral approach for the development of therapeutic and prophylactic vaccine against HBV and HCV.

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Year:  1999        PMID： 10516466     DOI： 10.1159/000024971

Source DB:  PubMed          Journal:  Intervirology        ISSN： 0300-5526            Impact factor:   1.763


  6 in total

1.  Maternally transferred antibodies from DNA-immunized avians protect offspring against hepadnavirus infection.

Authors:  C Rollier; C Charollois; C Jamard; C Trepo; L Cova
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

2.  Immunogenicity of recombinant hepatitis B vaccine in treatment-naive and treatment-experienced chronic hepatitis C patients: the effect of pegylated interferon plus ribavirin treatment.

Authors:  Ioannis-S Elefsiniotis; Elena Vezali; Konstantinos Kamposioras; Konstantinos-D Pantazis; Radostina Tontorova; Ioannis Ketikoglou; Antonios Moulakakis; George Saroglou
Journal:  World J Gastroenterol       Date:  2006-07-21       Impact factor: 5.742

3.  Prophylactic and therapeutic vaccination with dendritic cells against hepatitis C virus infection.

Authors:  J Encke; J Findeklee; J Geib; E Pfaff; W Stremmel
Journal:  Clin Exp Immunol       Date:  2005-11       Impact factor: 4.330

Review 4.  Hepatitis C virus and alcohol.

Authors:  Larry Siu; Julie Foont; Jack R Wands
Journal:  Semin Liver Dis       Date:  2009-04-22       Impact factor: 6.115

5.  Genetic vaccination with Flt3-L and GM-CSF as adjuvants: Enhancement of cellular and humoral immune responses that results in protective immunity in a murine model of hepatitis C virus infection.

Authors:  Jens Encke; Jomo Bernardin; Jasmin Geib; Gocha Barbakadze; Raymond Bujdoso; Wolfgang Stremmel
Journal:  World J Gastroenterol       Date:  2006-11-28       Impact factor: 5.742

6.  Evaluation of a novel non-penetrating electrode for use in DNA vaccination.

Authors:  Amy Donate; Domenico Coppola; Yolmari Cruz; Richard Heller
Journal:  PLoS One       Date:  2011-04-29       Impact factor: 3.240
  6 in total

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