Literature DB >> 10514332

New antimycobacterial saponin from Colubrina retusa.

H N ElSohly1, S Danner, X C Li, A C Nimrod, A M Clark.   

Abstract

A new jujubogenin saponin was isolated from the stems of Colubrina retusa and identified as jujubogenin 3-O-alpha-L-arabinofuranosyl (1-->2)-[3-O-(trans)-p-coumaroyl-beta-D-glucopyranosyl (1-->3)]-alpha-L-arabinopyranoside (4) on the basis of chemical and spectroscopic data. The antimycobacterial activity expressed as minimum inhibitory concentration (MIC) for compound 4 was 10 microg/mL.

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Year:  1999        PMID: 10514332     DOI: 10.1021/np9901940

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

1.  What's in a Name? Can Mullein Weed Beat TB Where Modern Drugs Are Failing?

Authors:  Eibhlín McCarthy; Jim M O'Mahony
Journal:  Evid Based Complement Alternat Med       Date:  2010-09-19       Impact factor: 2.629

Review 2.  Exploring the possible use of saponin adjuvants in COVID-19 vaccine.

Authors:  Rinku Sharma; Arivukarasu Palanisamy; Kuldeep Dhama; Gorakh Mal; Birbal Singh; Karam Pal Singh
Journal:  Hum Vaccin Immunother       Date:  2020-12-09       Impact factor: 3.452

3.  Phytochemical screening, antimycobacterial activity and acute toxicity of crude extracts of selected medicinal plant species used locally in the treatment of tuberculosis in Uganda.

Authors:  Benson Oloya; Jane Namukobe; Willy Ssengooba; Mathias Afayoa; Robert Byamukama
Journal:  Trop Med Health       Date:  2022-02-17
  3 in total

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