Literature DB >> 10514329

Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.

I P Singh1, K E Milligan, W H Gerwick.   

Abstract

A new brine-shrimp toxic and antifungal compound, tanikolide 1, has been isolated from the lipid extract of a Madagascan collection of the marine cyanobacterium Lyngbya majuscula. The structure of tanikolide was determined by spectroscopic methods, relying heavily on 2D NMR spectroscopy. The absolute configuration at C-5 of tanikolide was established as R by oxidizing the primary alcohol to an acid and analyzing the corresponding (R)- and (S)-PGME amide derivatives by (1)H NMR.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10514329     DOI： 10.1021/np990162c

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  19 in total

1.  Investigation of the Anti-Methicillin-Resistant Staphylococcus aureus Activity of (+)-Tanikolide- and (+)-Malyngolide-Based Analogues Prepared by Asymmetric Synthesis.

Authors:  Joseph Breheny; Cian Kingston; Robert Doran; Joao Anes; Marta Martins; Séamus Fanning; Patrick J Guiry
Journal:  Int J Mol Sci       Date:  2021-06-15       Impact factor: 5.923

2.  Pharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida Everglades.

Authors:  John P Berry; Miroslav Gantar; Robert E Gawley; Minglei Wang; Kathleen S Rein
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2004-12       Impact factor: 3.228

3.  Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula.

Authors:  Marcelino Gutiérrez; Kevin Tidgewell; Todd L Capson; Niclas Engene; Alejandro Almanza; Jörg Schemies; Manfred Jung; William H Gerwick
Journal:  J Nat Prod       Date:  2010-04-23       Impact factor: 4.050

4.  Microseiramide from the Freshwater Cyanobacterium Microseira sp. UIC 10445.

Authors:  Shangwen Luo; Aleksej Krunic; George E Chlipala; Jimmy Orjala
Journal:  Phytochem Lett       Date:  2015-09-01       Impact factor: 1.679

5.  Molluscicidal metabolites from an assemblage of Palmyra Atoll cyanobacteria.

Authors:  Alban R Pereira; Lena Etzbach; Niclas Engene; Rolf Müller; William H Gerwick
Journal:  J Nat Prod       Date:  2011-04-07       Impact factor: 4.050

6.  Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii.

Authors:  Alban R Pereira; Christine F McCue; William H Gerwick
Journal:  J Nat Prod       Date:  2010-02-26       Impact factor: 4.050

7.  Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula.

Authors:  Marcelino Gutiérrez; Eric H Andrianasolo; Won Kyo Shin; Douglas E Goeger; Alexandre Yokochi; Jörg Schemies; Manfred Jung; Dennis France; Susan Cornell-Kennon; Eun Lee; William H Gerwick
Journal:  J Org Chem       Date:  2009-08-07       Impact factor: 4.354

8.  Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway.

Authors:  Johanna Vestola; Tania K Shishido; Jouni Jokela; David P Fewer; Olli Aitio; Perttu Permi; Matti Wahlsten; Hao Wang; Leo Rouhiainen; Kaarina Sivonen
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-17       Impact factor: 11.205

Review 9.  Naturally occurring small molecule compounds that target histone deacetylases and their potential applications in cancer therapy.

Authors:  Yuki Maemoto; Yuki Shimizu; Ryu Katoh; Akihiro Ito
Journal:  J Antibiot (Tokyo)       Date:  2021-08-23       Impact factor: 2.649

10.  Oleic acid produced by a marine Vibrio spp. acts as an anti-Vibrio parahaemolyticus agent.

Authors:  Yanett Leyton; Jorge Borquez; José Darias; Mercedes Cueto; Ana R Díaz-Marrero; Carlos Riquelme
Journal:  Mar Drugs       Date:  2011-10-24       Impact factor: 6.085
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.