Literature DB >> 10511013

Drugs of abuse and brain gene expression.

G Torres1, J M Horowitz.   

Abstract

Addictive drugs like cocaine, ethanol, and morphine activate signal transduction pathways that regulate brain gene expression. Such regulation is modulated by the presence of certain transcription factor proteins present in a given neuron. This article summarizes the effects of several addictive drugs on transcriptional processes contributing to the development of a drug-dependent state. The characterization of drug-induced changes in gene expression shows promise for improving our understanding of drug-addiction phenomena and cellular modes of cocaine, ethanol, and morphine action.

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Year:  1999        PMID: 10511013     DOI: 10.1097/00006842-199909000-00007

Source DB:  PubMed          Journal:  Psychosom Med        ISSN: 0033-3174            Impact factor:   4.312


  8 in total

1.  Region-specific transcriptional response to chronic nicotine in rat brain.

Authors:  J K Kane; T Barrett; M P Vawter; R Chang; J Z Ma; D M Donovan; B Sharp; K G Becker; M D Li
Journal:  Brain Res       Date:  2001-08-03       Impact factor: 3.252

Review 2.  The opioid receptors as targets for drug abuse medication.

Authors:  Florence Noble; Magalie Lenoir; Nicolas Marie
Journal:  Br J Pharmacol       Date:  2015-06-26       Impact factor: 8.739

Review 3.  Nicotine addiction through a neurogenomic prism: ethics, public health, and smoking.

Authors:  Lorraine Caron; Katrina Karkazis; Thomas A Raffin; Gary Swan; Barbara A Koenig
Journal:  Nicotine Tob Res       Date:  2005-04       Impact factor: 4.244

Review 4.  Characterizing intercellular signaling peptides in drug addiction.

Authors:  Elena V Romanova; Nathan G Hatcher; Stanislav S Rubakhin; Jonathan V Sweedler
Journal:  Neuropharmacology       Date:  2008-08-03       Impact factor: 5.250

Review 5.  Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants.

Authors:  Heinz Steiner; Vincent Van Waes
Journal:  Prog Neurobiol       Date:  2012-10-17       Impact factor: 11.685

6.  Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a.

Authors:  Cagri T Unal; Joel A Beverley; Ingo Willuhn; Heinz Steiner
Journal:  Eur J Neurosci       Date:  2009-04       Impact factor: 3.386

7.  Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference.

Authors:  Han Zhang; Qisheng Wang; Qinmei Sun; Fenfen Qin; Dengyun Nie; Qian Li; Yun Gu; Yongwei Jiang; Shengfeng Lu; Zhigang Lu
Journal:  Cell Mol Neurobiol       Date:  2020-04-22       Impact factor: 5.046

8.  The neuropeptide Y Y1 receptor knockdown modulates activator protein 1-involved feeding behavior in amphetamine-treated rats.

Authors:  Yih-Shou Hsieh; Pei-Ni Chen; Ching-Han Yu; Jiuan-Miaw Liao; Dong-Yih Kuo
Journal:  Mol Brain       Date:  2013-11-13       Impact factor: 4.041

  8 in total

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