| Literature DB >> 10509915 |
A N Pae1, H Y Kim, H J Joo, B H Kim, Y S Cho, K I Choi, J H Choi, H Y Koh.
Abstract
Two series of oxazolidinone derivatives having substituted isoxazoles were synthesized and tested for antibacterial activities against several Gram-positive strains including the resistant strains of Staphylococcus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed in vitro activities (MIC) comparable or superior to the reference compound vancomycin.Entities:
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Year: 1999 PMID： 10509915 DOI： 10.1016/s0960-894x(99)00473-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823