Literature DB >> 10509503

Abrogation of post-myeloablative chemotherapy neutropenia by ex-vivo expanded autologous CD34-positive cells.

J Reiffers, C Cailliot, B Dazey, M Attal, J Caraux, J M Boiron.   

Abstract

We show that absolute and severe neutropenia after high-dose therapy with melphalan with or without total body irradiation can be abrogated by cells generated ex vivo. This may change the clinical practice of haematopoietic cell transplantation and high-dose chemotherapy because the morbidity and hospitalisation associated with neutropenia could be avoided or reduced.

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Year:  1999        PMID： 10509503     DOI： 10.1016/S0140-6736(99)03113-X

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  9 in total

1.  Optimizing hematopoietic recovery following bone marrow transplantation.

Authors:  Ronald Paquette; Kenneth Dorshkind
Journal:  J Clin Invest       Date:  2002-06       Impact factor: 14.808

2.  Hematopoietic stem cells in research and clinical applications: The "CD34 issue".

Authors:  Zoran Ivanovic
Journal:  World J Stem Cells       Date:  2010-04-26       Impact factor: 5.326

3.  Regulation of advanced therapy medicinal products will affect the practice of haematopoietic SCT in the near future: a perspective from the EBMT cell-processing committee.

Authors:  C Chabannon; M Hildebrandt; S Scheding; A Humpe; M Lowdell; I Slaper-Cortenbach
Journal:  Bone Marrow Transplant       Date:  2014-12-15       Impact factor: 5.483

4.  Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells.

Authors:  Kian-Ngiap Chua; Chou Chai; Peng-Chou Lee; Seeram Ramakrishna; Kam W Leong; Hai-Quan Mao
Journal:  Exp Hematol       Date:  2007-05       Impact factor: 3.084

Review 5.  Concise review: next-generation cell therapies to prevent infections in neutropenic patients.

Authors:  Marion E G Brunck; Lars K Nielsen
Journal:  Stem Cells Transl Med       Date:  2014-03-05       Impact factor: 6.940

6.  Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study.

Authors:  Jiafei Xi; Honghu Zhu; Daqing Liu; Xue Nan; Wen Zheng; Kaiyan Liu; Wei Shi; Lin Chen; Yang Lv; Fang Yan; Yanhua Li; Xiaoyan Xie; Yunfang Wang; Wen Yue; Xin Xu; Xiaofei Wei; Jun Zhu; Xiaojun Huang; Xuetao Pei
Journal:  PLoS One       Date:  2013-02-04       Impact factor: 3.240

7.  Application of proteoglycan extracted from the nasal cartilage of salmon heads for ex vivo expansion of hematopoietic progenitor cells derived from human umbilical cord blood.

Authors:  Ikuo Kashiwakura; Kenji Takahashi; Keiichi Takagaki
Journal:  Glycoconj J       Date:  2007-03-28       Impact factor: 3.009

8.  Optimal ex vivo expansion of neutrophils from PBSC CD34+ cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO.

Authors:  Olga Tura; G Robin Barclay; Huw Roddie; John Davies; Marc L Turner
Journal:  J Transl Med       Date:  2007-10-30       Impact factor: 5.531

9.  Rescuing Self: Transient Isolation and Autologous Transplantation of Bone Marrow Mitigates Radiation-Induced Hematopoietic Syndrome and Mortality in Mice.

Authors:  Subhajit Ghosh; Namita Indracanti; Jayadev Joshi; Prem Kumar Indraganti
Journal:  Front Immunol       Date:  2017-09-25       Impact factor: 7.561
  9 in total

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