| Literature DB >> 10508665 |
Z Wang1, W Fast, A M Valentine, S J Benkovic.
Abstract
This past year has produced determinations of X-ray crystal structures for three metallo-beta-lactamases and the elucidation of the catalytic mechanisms for a monozinc and a dizinc enzyme. These advances shed light on how such a diverse group of enzymes are evolving to inactivate so efficiently a broad spectrum of beta-lactam antibiotics.Entities:
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Year: 1999 PMID： 10508665 DOI： 10.1016/s1367-5931(99)00017-4
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822