Literature DB >> 10508631

Engineering the mouse genome by site-specific recombination.

D Metzger1, R Feil.   

Abstract

Site-specific recombination systems are powerful tools for introducing predetermined modifications into eukaryotic genomes. Recent advances allow the manipulation of chromosomal DNA in a spatially and temporally controlled manner in mice, offering unprecedented possibilities for studying mammalian genome function and for generating animal models for human diseases.

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Year:  1999        PMID： 10508631     DOI： 10.1016/s0958-1669(99)00012-9

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  33 in total

1.  Gene discovery and gene function assignment in filamentous fungi.

Authors:  L Hamer; K Adachi; M V Montenegro-Chamorro; M M Tanzer; S K Mahanty; C Lo; R W Tarpey; A R Skalchunes; R W Heiniger; S A Frank; B A Darveaux; D J Lampe; T M Slater; L Ramamurthy; T M DeZwaan; G H Nelson; J R Shuster; J Woessner; J E Hamer
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-10       Impact factor: 11.205

2.  Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells.

Authors:  A Loonstra; M Vooijs; H B Beverloo; B A Allak; E van Drunen; R Kanaar; A Berns; J Jonkers
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

3.  Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells.

Authors:  Susanne Andreas; Frieder Schwenk; Birgit Küter-Luks; Nicole Faust; Ralf Kühn
Journal:  Nucleic Acids Res       Date:  2002-06-01       Impact factor: 16.971

Review 4.  Cre/lox: one more step in the taming of the genome.

Authors:  Brian Sauer
Journal:  Endocrine       Date:  2002-12       Impact factor: 3.633

5.  A self-excising Cre recombinase allows efficient recombination of multiple ectopic heterospecific lox sites in transgenic tobacco.

Authors:  Ludmila Mlynárová; Jan-Peter Nap
Journal:  Transgenic Res       Date:  2003-02       Impact factor: 2.788

6.  Site-specific genomic targeting in Drosophila.

Authors:  Carsten Horn; Alfred M Handler
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-22       Impact factor: 11.205

7.  Approach sensitivity in the retina processed by a multifunctional neural circuit.

Authors:  Thomas A Münch; Rava Azeredo da Silveira; Sandra Siegert; Tim James Viney; Gautam B Awatramani; Botond Roska
Journal:  Nat Neurosci       Date:  2009-09-06       Impact factor: 24.884

8.  Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites.

Authors:  Vaibhao C Janbandhu; Daniel Moik; Reinhard Fässler
Journal:  Cell Cycle       Date:  2013-11-26       Impact factor: 4.534

9.  A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells.

Authors:  Wiebke Wolfsgruber; Susanne Feil; Sabine Brummer; Oliver Kuppinger; Franz Hofmann; Robert Feil
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-03       Impact factor: 11.205

10.  Selection of bacteriophage lambda integrases with altered recombination specificity by in vitro compartmentalization.

Authors:  Yvonne Tay; Candice Ho; Peter Droge; Farid J Ghadessy
Journal:  Nucleic Acids Res       Date:  2009-12-04       Impact factor: 16.971
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