Literature DB >> 10508600

T cells work together to fight cancer.

V Cerundolo1.   

Abstract

Recent studies have identified new melanoma antigens that are recognised by CD4(+) T cells. Analysis of tumour-specific CD4(+) T-cell responses may lead to the development of optimal anti-cancer vaccines that can induce an orchestrated effort of tumour-specific CD4(+) and CD8(+) T cells in the fight against cancer.

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Year:  1999        PMID： 10508600     DOI： 10.1016/s0960-9822(99)80442-4

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  2 in total

1.  MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.

Authors:  Valentina Robila; Marina Ostankovitch; Michelle L Altrich-Vanlith; Alexander C Theos; Sheila Drover; Michael S Marks; Nicholas Restifo; Victor H Engelhard
Journal:  J Immunol       Date:  2008-12-01       Impact factor: 5.422

2.  The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools.

Authors:  Satwinder Kaur Singh; Maaike Meyering; Tamara H Ramwadhdoebe; Linda F M Stynenbosch; Anke Redeker; Peter J K Kuppen; Cornelis J M Melief; Marij J P Welters; Sjoerd H van der Burg
Journal:  Cancer Immunol Immunother       Date:  2012-04-11       Impact factor: 6.968
  2 in total

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