Literature DB >> 10508425

Mixture-based synthetic combinatorial libraries.

R A Houghten1, C Pinilla, J R Appel, S E Blondelle, C T Dooley, J Eichler, A Nefzi, J M Ostresh.   

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Year:  1999        PMID： 10508425     DOI： 10.1021/jm990174v

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  56 in total

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2.  Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.

Authors:  Marc C Rideout; Jeffrey L Boldt; Gabriel Vahi-Ferguson; Peter Salamon; Adel Nefzi; John M Ostresh; Marc Giulianotti; Clemencia Pinilla; Anca M Segall
Journal:  Mol Divers       Date:  2011-09-22       Impact factor: 2.943

3.  Integrating computational and mixture-based screening of combinatorial libraries.

Authors:  Austin B Yongye; Clemencia Pinilla; Jose L Medina-Franco; Marc A Giulianotti; Colette T Dooley; Jon R Appel; Adel Nefzi; Thomas Scior; Richard A Houghten; Karina Martínez-Mayorga
Journal:  J Mol Model       Date:  2010-09-21       Impact factor: 1.810

4.  Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies.

Authors:  Austin B Yongye; Marc A Giulianotti; Adel Nefzi; Richard A Houghten; Karina Martínez-Mayorga
Journal:  J Comput Aided Mol Des       Date:  2010-03-24       Impact factor: 3.686

Review 5.  In vitro and direct in vivo testing of mixture-based combinatorial libraries for the identification of highly active and specific opiate ligands.

Authors:  Richard A Houghten; Colette T Dooley; Jon R Appel
Journal:  AAPS J       Date:  2006-05-26       Impact factor: 4.009

6.  Synergy and antagonism of promiscuous inhibition in multiple-compound mixtures.

Authors:  Brian Y Feng; Brian K Shoichet
Journal:  J Med Chem       Date:  2006-04-06       Impact factor: 7.446

7.  New peptide inhibitors of type IB topoisomerases: similarities and differences vis-a-vis inhibitors of tyrosine recombinases.

Authors:  David F Fujimoto; Clemencia Pinilla; Anca M Segall
Journal:  J Mol Biol       Date:  2006-08-24       Impact factor: 5.469

8.  Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.

Authors:  Clemencia Pinilla; Bruce S Edwards; Jon R Appel; Tina Yates-Gibbins; Marc A Giulianotti; Jose L Medina-Franco; Susan M Young; Radleigh G Santos; Larry A Sklar; Richard A Houghten
Journal:  Mol Pharmacol       Date:  2013-06-20       Impact factor: 4.436

9.  Synthetic small-molecule prohormone convertase 2 inhibitors.

Authors:  Dorota Kowalska; Jin Liu; Jon R Appel; Akihiko Ozawa; Adel Nefzi; Robert B Mackin; Richard A Houghten; Iris Lindberg
Journal:  Mol Pharmacol       Date:  2008-12-12       Impact factor: 4.436

10.  A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.

Authors:  Christopher J Armishaw; Narender Singh; Jose L Medina-Franco; Richard J Clark; Krystle C M Scott; Richard A Houghten; Anders A Jensen
Journal:  J Biol Chem       Date:  2009-11-09       Impact factor: 5.157
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