Literature DB >> 10508341

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Abstract

An exceptionally stable 1:2 complex [FeL(2)](3-) is formed from the ligand H(3)L and Fe(III). In contrast, the affinity of this ligand for other biometals is relatively small. These properties make H(3)L a highly promising candidate for medical applications (e.g. for the treatment of iron overload).

Entities:  

Year:  1999        PMID: 10508341

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  8 in total

1.  A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding.

Authors:  Filip Kielar; Qin Wang; Paul D Boyle; Katherine J Franz
Journal:  Inorganica Chim Acta       Date:  2012-12-01       Impact factor: 2.545

2.  Nucleotides and inorganic phosphates as potential antioxidants.

Authors:  Yael Richter; Bilha Fischer
Journal:  J Biol Inorg Chem       Date:  2006-08-01       Impact factor: 3.358

3.  Oligonucleotides are potent antioxidants acting primarily through metal ion chelation.

Authors:  Eyal Zobel; Eylon Yavin; Hugo E Gottlieb; Meirav Segal; Bilha Fischer
Journal:  J Biol Inorg Chem       Date:  2010-02-13       Impact factor: 3.358

4.  The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance of Pseudomonas aeruginosa.

Authors:  Amanda G Oglesby-Sherrouse; Louise Djapgne; Angela T Nguyen; Adriana I Vasil; Michael L Vasil
Journal:  Pathog Dis       Date:  2014-02-10       Impact factor: 3.166

5.  Synthesis and Study of Multifunctional Cyclodextrin-Deferasirox Hybrids.

Authors:  Jose Miguel Gascon; Valentina Oliveri; Andrew McGown; Ecem Kaya; Yu-Lin Chen; Carol Austin; Martin Walker; Frances M Platt; Graziella Vecchio; John Spencer
Journal:  ChemMedChem       Date:  2019-06-24       Impact factor: 3.466

Review 6.  Low-Molecular-Weight Fe(III) Complexes for MRI Contrast Agents.

Authors:  Shangjun Chen; Lu An; Shiping Yang
Journal:  Molecules       Date:  2022-07-18       Impact factor: 4.927

7.  Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Authors:  Douglas B Kell
Journal:  BMC Med Genomics       Date:  2009-01-08       Impact factor: 3.063

Review 8.  Clinical pharmacology of deferasirox.

Authors:  Chiaki Tanaka
Journal:  Clin Pharmacokinet       Date:  2014-08       Impact factor: 5.577

  8 in total

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