Literature DB >> 10508034

Association of alterations in ParC and GyrA proteins with resistance of clinical isolates of Enterococcus faecium to nine different fluoroquinolones.

S Brisse1, A C Fluit, U Wagner, P Heisig, D Milatovic, J Verhoef, S Scheuring, K Köhrer, F J Schmitz.   

Abstract

The parC and gyrA genes of 73 ciprofloxacin-resistant and 6 ciprofloxacin-susceptible Enterococcus faecium clinical isolates were partly sequenced. Alterations in ParC and GyrA, possibly in combination with other resistance mechanisms, severely restricted the in vitro activities of the nine quinolones tested. For all isolates, clinafloxacin and sitafloxacin showed the best activities.

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Year:  1999        PMID： 10508034      PMCID： PMC89510          DOI： 10.1128/AAC.43.10.2513

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  30 in total

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2.  Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.

Authors:  M J Gill; N P Brenwald; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

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Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191

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Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-06       Impact factor: 3.267

6.  Alterations in topoisomerase IV and DNA gyrase in quinolone-resistant mutants of Mycoplasma hominis obtained in vitro.

Authors:  C M Bébéar; H Renaudin; A Charron; J M Bové; C Bébéar; J Renaudin
Journal:  Antimicrob Agents Chemother       Date:  1998-09       Impact factor: 5.191

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Authors:  H Yoshida; M Bogaki; M Nakamura; S Nakamura
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

8.  Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome.

Authors:  E Y Ng; M Trucksis; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

9.  In vitro activities of quinolones against enterococci resistant to penicillin-aminoglycoside synergy.

Authors:  D F Sahm; G T Koburov
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

10.  Primary targets of fluoroquinolones in Streptococcus pneumoniae.

Authors:  H Fukuda; K Hiramatsu
Journal:  Antimicrob Agents Chemother       Date:  1999-02       Impact factor: 5.191
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  6 in total

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Review 2.  Gatifloxacin: a review of its use in the management of bacterial infections.

Authors:  Caroline M Perry; Douglas Ormrod; Miriam Hurst; Susan V Onrust
Journal:  Drugs       Date:  2002       Impact factor: 9.546

3.  Antibiotic resistances of starter and probiotic strains of lactic acid bacteria.

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Journal:  Appl Environ Microbiol       Date:  2006-11-22       Impact factor: 4.792

4.  High-level ciprofloxacin resistance from point mutations in gyrA and parC confined to global hospital-adapted clonal lineage CC17 of Enterococcus faecium.

Authors:  Helen L Leavis; Rob J L Willems; Janetta Top; Marc J M Bonten
Journal:  J Clin Microbiol       Date:  2006-03       Impact factor: 5.948

5.  Association of mutation patterns in GyrA and ParC genes with quinolone resistance levels in lactic acid bacteria.

Authors:  Shaoying Li; Zhen Li; Wan Wei; Chunyan Ma; Xiaomin Song; Shufen Li; Wenying He; Jianjun Tian; Xiaoyan Huo
Journal:  J Antibiot (Tokyo)       Date:  2014-09-10       Impact factor: 2.649

6.  Identification and characterization of resistance and pathogenicity of Enterococcus spp. in samples of donor breast milk.

Authors:  Luana Andrade Mendes Santana; Nívea Nara Novais Andrade; Lucas Santana Coelho da Silva; Caline Novais Teixeira Oliveira; Breno Bittencourt de Brito; Fabrício Freire de Melo; Cláudio Lima Souza; Lucas Miranda Marques; Márcio Vasconcelos Oliveira
Journal:  World J Clin Pediatr       Date:  2020-11-19
  6 in total

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