Literature DB >> 10507686

Im-trityl protection of histidine.

S J Harding1, J H Jones, A N Sabirov, V V Samukov.   

Abstract

A rational attempt to prepare FmocHis(piTrt)OH regiospecifically gave in fact the well-known tau-trityl isomer, and experiments with model systems indicate that the prospects for access to pi-trityl histidine derivatives, which would be of great value for the racemization-free synthesis of histidine-containing peptides, are poor.

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Year:  1999        PMID: 10507686     DOI: 10.1002/(SICI)1099-1387(199908)5:8<368::AID-PSC210>3.0.CO;2-P

Source DB:  PubMed          Journal:  J Pept Sci        ISSN: 1075-2617            Impact factor:   1.905


  1 in total

1.  Copper-peptide complex structure and reactivity when found in conserved His-X(aa)-His sequences.

Authors:  Ga Young Park; Jung Yoon Lee; Richard A Himes; Gnana S Thomas; Ninian J Blackburn; Kenneth D Karlin
Journal:  J Am Chem Soc       Date:  2014-08-29       Impact factor: 15.419

  1 in total

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