Literature DB >> 10501856

Effective cancer therapy with a single injection of interleukin-2 at the site of the tumour.

W D Otter1, J Cadée, R Gavhumende, C J De Groot, W E Hennink, R Stewart.   

Abstract

Mice with a severe metastasized tumour burden can be cured with a single local injection of interleukin-2. Such a treatment can also be effective against ocular squamous cell carcinoma in cows and transmissible venereal tumours in dogs. We did not notice any toxic effects of this treatment.

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Year:  1999        PMID： 10501856     DOI： 10.1007/s002620050595

Source DB:  PubMed          Journal:  Cancer Immunol Immunother        ISSN： 0340-7004            Impact factor:   6.968


  3 in total

1.  Intratumoral recombinant human interferon alpha-2a and vincristine combination therapy in canine transmissible venereal tumour.

Authors:  Halit Kanca; Gizem Tez; Kazim Bal; Dogukan Ozen; Eray Alcigir; Sevil Atalay Vural
Journal:  Vet Med Sci       Date:  2018-08-17

2.  The effect of interleukin-2 on canine peripheral nerve sheath tumours after marginal surgical excision: a double-blind randomized study.

Authors:  Annika N Haagsman; Astrid C S Witkamp; Bart E Sjollema; Marja J L Kik; Jolle Kirpensteijn
Journal:  BMC Vet Res       Date:  2013-08-08       Impact factor: 2.741

3.  Local therapy of cancer with free IL-2.

Authors:  Willem Den Otter; John J L Jacobs; Jan J Battermann; Gerrit Jan Hordijk; Zachary Krastev; Ekaterina V Moiseeva; Rachel J E Stewart; Paul G P M Ziekman; Jan Willem Koten
Journal:  Cancer Immunol Immunother       Date:  2008-07       Impact factor: 6.968
  3 in total

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