Literature DB >> 10499277

Proteolytic cleavage of the repressor (BlaI) of beta-lactamase synthesis in Staphylococcus aureus.

R A Lewis1, S P Curnock, K G Dyke.   

Abstract

The proteolytic cleavage of BlaI was shown to correlate with beta-lactamase synthesis in Staphylococcus aureus. BlaI was found to be autoregulatory when expressed from the blaZ promoter. Insertion of a 10-bp linker into the SnaBI site of blaRI resulted in constitutive synthesis of beta-lactamase.

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Year:  1999        PMID: 10499277     DOI: 10.1111/j.1574-6968.1999.tb08687.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN: 0378-1097            Impact factor:   2.742


  5 in total

1.  Binding of the gene repressor BlaI to the bla operon in methicillin-resistant Staphylococcus aureus.

Authors:  Leticia I Llarrull; Mary Prorok; Shahriar Mobashery
Journal:  Biochemistry       Date:  2010-09-21       Impact factor: 3.162

2.  Dissection of events in the resistance to β-lactam antibiotics mediated by the protein BlaR1 from Staphylococcus aureus.

Authors:  Leticia I Llarrull; Shahriar Mobashery
Journal:  Biochemistry       Date:  2012-05-29       Impact factor: 3.162

Review 3.  Response of gram-positive bacteria to copper stress.

Authors:  Marc Solioz; Helge K Abicht; Mélanie Mermod; Stefano Mancini
Journal:  J Biol Inorg Chem       Date:  2009-09-23       Impact factor: 3.358

4.  Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strain.

Authors:  Yahua Chen; Janice Succi; Fred C Tenover; Theresa M Koehler
Journal:  J Bacteriol       Date:  2003-02       Impact factor: 3.490

5.  Redefining the role of the β-lactamase locus in methicillin-resistant Staphylococcus aureus: β-lactamase regulators disrupt the MecI-mediated strong repression on mecA and optimize the phenotypic expression of resistance in strains with constitutive mecA expression.

Authors:  Pedro Arêde; Joana Ministro; Duarte C Oliveira
Journal:  Antimicrob Agents Chemother       Date:  2013-04-15       Impact factor: 5.191

  5 in total

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