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Literature DB >> 10498919

Designing dendrimers for drug delivery.

Abstract

Dendrimers are highly branched three-dimensional macromolecules with highly controlled structures, a single molecular weight, a large number of controllable 'peripheral' functionalities and a tendency to adopt a globular shape once a certain size is reached. These features have made their application in pharmaceutical and medicinal chemistry particularly attractive. This review briefly discusses the preparation of dendrimers, their use as gene delivery agents and magnetic resonance imaging agents, and their potential for applications in drug delivery.

Year: 1999 PMID： 10498919 DOI： 10.1016/s1461-5347(99)00203-5

Source DB: PubMed Journal: Pharm Sci Technol Today ISSN： 1461-5347

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Cited

38 in total

1. Medicine on a small scale.

Authors: Marijeta Kralj; Kresimir Pavelic
Journal: EMBO Rep Date: 2003-11 Impact factor: 8.807

2. Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery.

Authors: Quan Yuan; Eunmee Lee; W Andrew Yeudall; Hu Yang
Journal: Oral Oncol Date: 2010-08-21 Impact factor: 5.337

3. Design and exploratory data analysis of a second generation of dendrimer prodrugs potentially antichagasic and leishmanicide.

Authors: Jeanine Giarolla; Kerly Fernanda Mesquita Pasqualoto; Elizabeth I Ferreira
Journal: Mol Divers Date: 2013-08-29 Impact factor: 2.943

4. Electrospun blends of gelatin and gelatin-dendrimer conjugates as a wound-dressing and drug-delivery platform.

Authors: Alpana A Dongargaonkar; Gary L Bowlin; Hu Yang
Journal: Biomacromolecules Date: 2013-10-30 Impact factor: 6.988

Review 5. Enabling individualized therapy through nanotechnology.

Authors: Jason H Sakamoto; Anne L van de Ven; Biana Godin; Elvin Blanco; Rita E Serda; Alessandro Grattoni; Arturas Ziemys; Ali Bouamrani; Tony Hu; Shivakumar I Ranganathan; Enrica De Rosa; Jonathan O Martinez; Christine A Smid; Rachel M Buchanan; Sei-Young Lee; Srimeenakshi Srinivasan; Matthew Landry; Anne Meyn; Ennio Tasciotti; Xuewu Liu; Paolo Decuzzi; Mauro Ferrari
Journal: Pharmacol Res Date: 2010-01-05 Impact factor: 7.658

Designing dendrimers for drug delivery.

1. Medicine on a small scale.

2. Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery.

3. Design and exploratory data analysis of a second generation of dendrimer prodrugs potentially antichagasic and leishmanicide.

4. Electrospun blends of gelatin and gelatin-dendrimer conjugates as a wound-dressing and drug-delivery platform.

Review 5. Enabling individualized therapy through nanotechnology.

Review 6. Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry.

7. Biodegradable polydisulfide dendrimer nanoclusters as MRI contrast agents.

8. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas.

9. Stealth dendrimers for drug delivery: correlation between PEGylation, cytocompatibility, and drug payload.

10. Click hybridization of immune cells and polyamidoamine dendrimers.