| Literature DB >> 10498195 |
M G Russell1, M S Beer, J A Stanton, B Sohal, R J Mortishire-Smith, J L Castro.
Abstract
The conformational restriction of a (benzylamino)methyl substituted pyrrolidine to form 2,7-diazabicyclo[3.3.0]octanes has led to a series of compounds with high affinity at the h5-HT1D receptor as well as dramatically increased concentrations in the hepatic portal vein following oral administration.Entities:
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Year: 1999 PMID： 10498195 DOI： 10.1016/s0960-894x(99)00409-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823