BACKGROUND: Nosocomial infections with influenza virus are rarely recognized in neonatal intensive care units (NICU). An outbreak of influenza A virus infection in the NICU of an urban county hospital during the 1997 to 1998 influenza season is reported. METHODS: Clinical and virologic data were recorded in all symptomatic NICU patients after influenza A infection was diagnosed in one infant in October, 1997. RESULTS: Influenza A/H3N2 was isolated from two of four symptomatic infants. The application of rapid diagnostic techniques for the characterization of influenza virus infection allowed the timely institution of basic infection control measures, limiting this outbreak. Resistance to amantadine was documented for the first time in this patient population by reverse transcription-PCR within 48 h of treatment in one case. CONCLUSIONS: Prevention by immunization is a priority in those caring for high risk NICU patients.
BACKGROUND:Nosocomial infections with influenza virus are rarely recognized in neonatal intensive care units (NICU). An outbreak of influenza A virus infection in the NICU of an urban county hospital during the 1997 to 1998 influenza season is reported. METHODS: Clinical and virologic data were recorded in all symptomatic NICU patients after influenza A infection was diagnosed in one infant in October, 1997. RESULTS:InfluenzaA/H3N2 was isolated from two of four symptomatic infants. The application of rapid diagnostic techniques for the characterization of influenza virus infection allowed the timely institution of basic infection control measures, limiting this outbreak. Resistance to amantadine was documented for the first time in this patient population by reverse transcription-PCR within 48 h of treatment in one case. CONCLUSIONS: Prevention by immunization is a priority in those caring for high risk NICU patients.
Authors: Navin K Vij; Christopher C Stryker; Frank P Esper; Michael R Jacobs; Blanca E Gonzalez Journal: Pediatrics Date: 2011-10-03 Impact factor: 7.124
Authors: F Stripeli; Z Sakkou; N Papadopoulos; V Georgiou; P Gratsia; I Christodoulou; M Tsolia Journal: Eur J Clin Microbiol Infect Dis Date: 2010-03-27 Impact factor: 3.267
Authors: David W Kimberlin; Edward P Acosta; Mark N Prichard; Pablo J Sánchez; Krow Ampofo; David Lang; Negar Ashouri; John A Vanchiere; Mark J Abzug; Nazha Abughali; Mary T Caserta; Janet A Englund; Sunil K Sood; Michael G Spigarelli; John S Bradley; Judy Lew; Marian G Michaels; Wen Wan; Gretchen Cloud; Penelope Jester; Fred D Lakeman; Richard J Whitley Journal: J Infect Dis Date: 2012-12-10 Impact factor: 5.226
Authors: Joseph F Standing; Angela Nika; Vasileios Tsagris; Ioannis Kapetanakis; Helena C Maltezou; Dimitris A Kafetzis; Maria N Tsolia Journal: Antimicrob Agents Chemother Date: 2012-05-07 Impact factor: 5.191
Authors: Joanne E Enstone; Puja R Myles; Peter J M Openshaw; Elaine M Gadd; Wei Shen Lim; Malcolm G Semple; Robert C Read; Bruce L Taylor; James McMenamin; Colin Armstrong; Barbara Bannister; Karl G Nicholson; Jonathan S Nguyen-Van-Tam Journal: Emerg Infect Dis Date: 2011-04 Impact factor: 6.883
Authors: Ji Hyeon Baek; Yu Bin Seo; Won Suk Choi; Sae Yoon Kee; Hye Won Jeong; Hee Young Lee; Byung Wook Eun; Eun Ju Choo; Jacob Lee; Sung Ran Kim; Young Keun Kim; Joon Young Song; Seong-Heon Wie; Jin-Soo Lee; Hee Jin Cheong; Woo Joo Kim Journal: Korean J Intern Med Date: 2014-02-27 Impact factor: 2.884