Literature DB >> 10491996

Gas chromatographic-mass spectrometric analysis of urinary sugar and sugar alcohols during pregnancy.

M Tetsuo1, C Zhang, H Matsumoto, I Matsumoto.   

Abstract

A refined and simplified method has been developed for the simultaneous analysis of urinary sugar and sugar alcohols after urease treatment by using capillary gas chromatography-mass spectrometry (GC-MS). Since carbohydrate metabolism during pregnancy is considered to be diabetogenic, our interest has been concentrated on understanding the mechanism of the metabolic deviation by assessing the glucose excursion and glucose fluxes. The present study suggests that changes of the levels of glucose, sorbitol, fructose, myo-inositol, and 1,5-anhydro-D-glucitol (1,5-AG) may reflect a mild alteration in carbohydrate metabolism that goes undetected by conventional diabetic indicators.

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Year:  1999        PMID: 10491996     DOI: 10.1016/s0378-4347(99)00209-1

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Sci Appl        ISSN: 1387-2273


  7 in total

1.  Analysis of polyols in urine by liquid chromatography-tandem mass spectrometry: a useful tool for recognition of inborn errors affecting polyol metabolism.

Authors:  M M C Wamelink; D E C Smith; C Jakobs; N M Verhoeven
Journal:  J Inherit Metab Dis       Date:  2005       Impact factor: 4.982

2.  Sensitive LC MS quantitative analysis of carbohydrates by Cs+ attachment.

Authors:  Eduard Rogatsky; Harsha Jayatillake; Gayotri Goswami; Vlad Tomuta; Daniel Stein
Journal:  J Am Soc Mass Spectrom       Date:  2005-09-22       Impact factor: 3.109

3.  The perinatal transition of the circulating metabolome in a nonhuman primate.

Authors:  Andrew C Beckstrom; Pattaraporn Tanya; Elizabeth M Humston; Laura R Snyder; Robert E Synovec; Sandra E Juul
Journal:  Pediatr Res       Date:  2012-02-15       Impact factor: 3.756

4.  Quantitative analysis of myo-inositol in urine, blood and nutritional supplements by high-performance liquid chromatography tandem mass spectrometry.

Authors:  Kit-Yi Leung; Kevin Mills; Katie A Burren; Andrew J Copp; Nicholas D E Greene
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2011-08-06       Impact factor: 3.205

5.  Multiple-reaction monitoring liquid chromatography mass spectrometry for monosaccharide compositional analysis of glycoproteins.

Authors:  Loubna A Hammad; Marwa M Saleh; Milos V Novotny; Yehia Mechref
Journal:  J Am Soc Mass Spectrom       Date:  2009-02-24       Impact factor: 3.109

6.  Urinary levoglucosan as a biomarker of wood smoke exposure: observations in a mouse model and in children.

Authors:  Christopher T Migliaccio; Megan A Bergauff; Christopher P Palmer; Forrest Jessop; Curtis W Noonan; Tony J Ward
Journal:  Environ Health Perspect       Date:  2008-08-15       Impact factor: 9.031

7.  Determination of oligosaccharides and monosaccharides in Hakka rice wine by precolumn derivation high-performance liquid chromatography.

Authors:  Weidong Bai; Xiaodi Fang; Wenhong Zhao; Shiqi Huang; Hongkang Zhang; Min Qian
Journal:  J Food Drug Anal       Date:  2015-07-23       Impact factor: 6.157

  7 in total

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