Literature DB >> 10490441

Are glomerular filtration rate estimations necessary before high dose methotrexate?

H Rees1, I M Hann, J M Chessells, D K Webb.   

Abstract

Glomerular filtration rates (GFR) were estimated in 168 children (227 estimates) before treatment for haematological malignancies with high dose, intravenous methotrexate. Clinical management was altered on the basis of GFR in only two cases, both of whom had tumour lysis syndrome. Routine estimations of GFR do not contribute to management.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10490441      PMCID: PMC1718091          DOI: 10.1136/adc.81.4.339

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  3 in total

Review 1.  The clinical pharmacology of methotrexate: new applications of an old drug.

Authors:  W A Bleyer
Journal:  Cancer       Date:  1978-01       Impact factor: 6.860

2.  Intensification of treatment and survival in all children with lymphoblastic leukaemia: results of UK Medical Research Council trial UKALL X. Medical Research Council Working Party on Childhood Leukaemia.

Authors:  J M Chessells; C Bailey; S M Richards
Journal:  Lancet       Date:  1995-01-21       Impact factor: 79.321

3.  Improved cure rate in children with B-cell acute lymphoblastic leukaemia (B-ALL) and stage IV B-cell non-Hodgkin's lymphoma (B-NHL)--results of the UKCCSG 9003 protocol.

Authors:  A Atra; M Gerrard; R Hobson; J D Imeson; S Ashley; C R Pinkerton
Journal:  Br J Cancer       Date:  1998-06       Impact factor: 7.640

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.