Literature DB >> 10489881

Anti-platelet aggregation activity of stilbene derivatives from Rheum undulatum.

S K Ko1, S M Lee, W K Whang.   

Abstract

In continued studies on cultivated Korean rhubarb rhizomes (Rheum undulatum), three known stilbenes (desoxyrhapontigenin, rhapontigenin, piceatannol) have been screened for activity on blood platelet aggregation. Both rhapontigenin and desoxyrhapontigenin exhibited strong inhibition on the aggregation induced by arachidonic acid and collagen. However, piceatannol did not show inhibition. These inhibitory effects may partially contribute to anti-blood stagnancy activity of rhubarb.

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Year:  1999        PMID： 10489881     DOI： 10.1007/BF02979065

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  8 in total

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Journal:  Int J Clin Exp Med       Date:  2015-11-15

2.  Stilbenes contribute to the anticancer effects of Rheum undulatum L. through activation of apoptosis.

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Journal:  Oncol Lett       Date:  2019-01-14       Impact factor: 2.967

3.  Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenes.

Authors:  Oanh Dang; Lorena Navarro; Michael David
Journal:  Shock       Date:  2004-05       Impact factor: 3.454

4.  Screening of Korean medicinal plants for possible osteoclastogenesis effects in vitro.

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Journal:  Genes Nutr       Date:  2008-02       Impact factor: 5.523

5.  1-Methyl-2-[(E)-2,4,5-trimeth-oxy-styr-yl]-pyridinium benzene-sulfonate mono-hydrate.

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6.  In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.

Authors:  Dahae Lee; SeonJu Park; Sungyoul Choi; Seung Hyun Kim; Ki Sung Kang
Journal:  Molecules       Date:  2018-05-18       Impact factor: 4.411

7.  Rhaponticin decreases the metastatic and angiogenic abilities of cancer cells via suppression of the HIF‑1α pathway.

Authors:  Aeyung Kim; Jin Yeul Ma
Journal:  Int J Oncol       Date:  2018-07-11       Impact factor: 5.650

8.  Arginase inhibition by rhaponticin increases L-arginine concentration that contributes to Ca2+-dependent eNOS activation.

Authors:  Bon-Hyeock Koo; Jonghoon Lee; Younghyun Jin; Hyun Kyo Lim; Sungwoo Ryoo
Journal:  BMB Rep       Date:  2021-10       Impact factor: 4.778
  8 in total

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