Literature DB >> 10487437

An unreported side effect of topical clarithromycin when used successfully to treat Mycobacterium avium-intracellulare keratitis.

A K Tyagi1, V V Kayarkar, P J McDonnell.   

Abstract

PURPOSE: To report a case of Mycobacterium avium-intracellulare (MAI) keratitis successfully treated with topical clarithromycin. An unreported side effect of the topical medication is described.
METHODS: A regular follow-up in the corneal clinic was arranged, and a pertinent literature search performed.
RESULTS: The use of topical clarithromycin was successful in treating the keratitis. The patient did not complain of any ocular discomfort. Corneal subepithelial deposits that appeared during treatment with clarithromycin resolved shortly after the therapy was discontinued.
CONCLUSION: This case report demonstrates that a rare infection like MAI keratitis can be successfully treated with topical clarithromycin. It also highlights the possible corneal deposition of this drug, which resolved after cessation of therapy.

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Year:  1999        PMID: 10487437

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  2 in total

Review 1.  Nontuberculous Mycobacterial Ocular Infections: A Systematic Review of the Literature.

Authors:  Wajiha J Kheir; Huda Sheheitli; Maamoun Abdul Fattah; Rola N Hamam
Journal:  Biomed Res Int       Date:  2015-05-27       Impact factor: 3.411

Review 2.  Delayed onset Mycobacterium intracellulare keratitis after laser in situ keratomileusis: A case report and literature review.

Authors:  JaeSang Ko; Se Kyung Kim; Dong Eun Yong; Tae-Im Kim; Eung Kweon Kim
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

  2 in total

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