Literature DB >> 10486908

Compounds labelled with short-lived beta(+)-emitting radionuclides and some applications in life sciences. The importance of time as a parameter.

B Långström1, T Kihlberg, M Bergström, G Antoni, M Björkman, B H Forngren, T Forngren, P Hartvig, K Markides, U Yngve, M Ogren.   

Abstract

Some examples of recent development of the synthesis of compounds labelled with short-lived beta(+)-emitting radionuclides will be discussed with an emphasis on the importance of time in selecting a synthetic strategy. Furthermore the use of such labelled compounds to monitor certain processes in areas within the field of analytical chemistry and in various applications in drug development will be presented.

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Year:  1999        PMID: 10486908     DOI: 10.3891/acta.chem.scand.53-0651

Source DB:  PubMed          Journal:  Acta Chem Scand        ISSN: 0904-213X


  5 in total

1.  Radiolabeled oligonucleotides for antisense imaging.

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Journal:  Curr Org Synth       Date:  2011-08-01       Impact factor: 1.975

Review 2.  Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development.

Authors:  Mats Bergström; Anders Grahnén; Bengt Långström
Journal:  Eur J Clin Pharmacol       Date:  2003-08-22       Impact factor: 2.953

3.  One-pot, direct incorporation of [11C]CO2 into carbamates.

Authors:  Jacob M Hooker; Achim T Reibel; Sidney M Hill; Michael J Schueller; Joanna S Fowler
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

4.  Synthesis of two potential NK1-receptor ligands using [1-11C]ethyl iodide and [1-11C]propyl iodide and initial PET-imaging.

Authors:  Stina Syvänen; Jonas Eriksson; Tove Genchel; Orjan Lindhe; Gunnar Antoni; Bengt Långström
Journal:  BMC Med Imaging       Date:  2007-07-30       Impact factor: 1.930

5.  Fully-automated radiosynthesis of the amyloid tracer [11C] PiB via direct [11C]CO2 fixation-reduction.

Authors:  Pablo Buccino; Eduardo Savio; Williams Porcal
Journal:  EJNMMI Radiopharm Chem       Date:  2019-07-16
  5 in total

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