J L Stéphan1, C Galambrun, A Dutour, F Freycon. 1. Paediatric Haematology and Oncology Unit, Hôpital Nord, Saint Etienne, F-42055, Cx02, France. jlstephan@infonie.fr
Abstract
UNLABELLED: We present the case of a breast-fed 5-month-old infant who presented with pancytopenia, secondary to intense myelofibrosis during the winter months because of undiagnosed rickets. The patient responded to oral vitamin D with rapid resolution of symptoms. Secondary hyperparathyroidism was the probable cause of the myelofibrosis. CONCLUSION: Although nutritional rickets remains a problem in developing countries, children in northern climates in industrialized countries may also be at risk. Rickets must be considered when assessing myelofibrosis in a very young child.
UNLABELLED: We present the case of a breast-fed 5-month-old infant who presented with pancytopenia, secondary to intense myelofibrosis during the winter months because of undiagnosed rickets. The patient responded to oral vitamin D with rapid resolution of symptoms. Secondary hyperparathyroidism was the probable cause of the myelofibrosis. CONCLUSION: Although nutritional rickets remains a problem in developing countries, children in northern climates in industrialized countries may also be at risk. Rickets must be considered when assessing myelofibrosis in a very young child.
Authors: Remya Rajan; Immanuel Paul; Kripa Elizabeth Cherian; Anu Korula; Julie Hephzibah; Marie Therese Manipadam; Deepak Thomas Abraham; Nitin Kapoor; Thomas Vizhalil Paul Journal: AACE Clin Case Rep Date: 2020-12-28