Literature DB >> 10483695

[Value of mistletoe lectin standardized mistletoe extract for evaluating antitumor properties].

U Mengs1, K Witthohn, T Schwarz, H Lentzen.   

Abstract

It could be shown from several experiments that carbohydrate-binding mistletoe lectins represent the pharmacologically active constituents of mistletoe extracts. On the basis of these findings, it was possible to develop an extract preparation standardized with respect to the mistletoe lectin concentration. This drug is the first mistletoe preparation that fulfills the criteria of the guidelines for the development of drugs (1) regarding its quality and stability of the active ingredients under certain storage conditions. The quality of this preparation has also been shown in several animal models to demonstrate antitumoral potencies.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10483695

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  1 in total

1.  Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells.

Authors:  Yau Sang Chan; Jack Ho Wong; Evandro Fei Fang; Wenliang Pan; Tzi Bun Ng
Journal:  PLoS One       Date:  2012-06-14       Impact factor: 3.240

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.