| Literature DB >> 10482454 |
A Martínez1, A I Esteban, A Herrero, C Ochoa, G Andrei, R Snoeck, J Balzarini, E De Clercq.
Abstract
A new series of imidazothiadiazine dioxides, including the first acyclonucleosides derived from this heterocycle moiety, has been synthesized. A wide-spectrum antiviral screening was performed. Some of the N-1 benzyl imidazothiadiazines and the new acyclonucleosides showed interesting anti-CMV or anti-HIV activity. These structures could be considered as new lead compounds for antiviral drug research.Entities:
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Year: 1999 PMID： 10482454 DOI： 10.1016/s0968-0896(99)00114-5
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641