| Literature DB >> 10481406 |
T Takahashi1, H Taguchi, H Yamaguchi, T Osaki, S Sato, M Kamei, S Hashizume, S Kamiya.
Abstract
The antimicrobial activities of aqueous cacao mass extract against enterohemorrhagic Escherichia coli (EHEC) O157:H7 006 strain were studied. Hot water extract of cacao mass (cocoa extract) was shown to inhibit the growth of EHEC O157:H7 006 strain in PBS or CAYE medium. In addition, the production of verotoxins (types 1 and 2) of EHEC O157:H7 006 strain was significantly inhibited by 8.0% cocoa extract. The cocoa extract did not neutralize the cytotoxity of verotoxins, but had inhibitory effect on adhesion of verotoxins to the target Vero cells. These results demonstrate that cacao mass has antimicrobial effects on EHEC O157:H7.Entities:
Mesh:
Substances:
Year: 1999 PMID: 10481406 DOI: 10.11150/kansenshogakuzasshi1970.73.694
Source DB: PubMed Journal: Kansenshogaku Zasshi ISSN: 0387-5911