Literature DB >> 10479768

Triterpene antioxidants from ganoderma lucidum.

M Zhu1, Q Chang, L K Wong, F S Chong, R C Li.   

Abstract

Ganoderma lucidum was studied for its antioxidative activity by bioassay guided isolation in conjunction with in vitro tests. The powdered crude drug was treated with boiling water and the aqueous extract (Ex1) was further separated to obtain terpene and polysaccharide fractions. The two fractions and Ex1 were screened for their antioxidative effect against pyrogallol induced erythrocyte membrane oxidation and Fe (II)-ascorbic acid induced lipid peroxidation. All tested samples showed antioxidative activities in a dose dependent manner and the terpene fraction was found to possess the highest effect compared with the others. Chemical isolation of the terpene fraction resulted in the detection of ganoderic acids A, B, C and D, lucidenic acid B and ganodermanontriol as major ingredients. Copyright 1999 John Wiley & Sons, Ltd.

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Year:  1999        PMID： 10479768     DOI： 10.1002/(sici)1099-1573(199909)13:6<529::aid-ptr481>3.0.co;2-x

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  31 in total

1.  Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.

Authors:  Toshitaka Kohno; Tran Hai-Bang; Qinchang Zhu; Yhiya Amen; Seiichi Sakamoto; Hiroyuki Tanaka; Satoshi Morimoto; Kuniyoshi Shimizu
Journal:  J Nat Med       Date:  2017-01-11       Impact factor: 2.343

2.  Analysis of triterpenoids in ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry.

Authors:  Min Yang; Xiaoming Wang; Shuhong Guan; Jiameng Xia; Jianghao Sun; Hui Guo; De-An Guo
Journal:  J Am Soc Mass Spectrom       Date:  2007-03-26       Impact factor: 3.109

Review 3.  Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling.

Authors:  Balraj Singh Gill; Prateek Sharma; Raj Kumar; Sanjeev Kumar
Journal:  Tumour Biol       Date:  2015-12-30

4.  Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages.

Authors:  Connie W H Woo; Ricky Y K Man; Yaw L Siow; Patrick C Choy; Eric W Y Wan; Chak S Lau; Karmin O
Journal:  Mol Cell Biochem       Date:  2005-07       Impact factor: 3.396

5.  A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma.

Authors:  Azim Hossain; Faisal F Y Radwan; Bently P Doonan; Jason M God; Lixia Zhang; P Darwin Bell; Azizul Haque
Journal:  Apoptosis       Date:  2012-10       Impact factor: 4.677

6.  Apoptotic and Immune Restoration Effects of Ganoderic Acids Define a New Prospective for Complementary Treatment of Cancer.

Authors:  Faisal F Y Radwan; J Manuel Perez; Azizul Haque
Journal:  J Clin Cell Immunol       Date:  2011-12-11

7.  Evaluation of Pb (II) biosorption utilizing sugarcane bagasse colonized by Basidiomycetes.

Authors:  D Palin; K B Rufato; G A Linde; N B Colauto; J Caetano; O Alberton; D A Jesus; D C Dragunski
Journal:  Environ Monit Assess       Date:  2016-04-11       Impact factor: 2.513

8.  Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats.

Authors:  Wen-Chuan Lin; Wei-Lii Lin
Journal:  World J Gastroenterol       Date:  2006-01-14       Impact factor: 5.742

9.  Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3.

Authors:  Zhe Ji; Qingjiu Tang; Ruixia Hao; Jinsong Zhang; Yingjie Pan
Journal:  Oncol Lett       Date:  2011-03-21       Impact factor: 2.967

10.  Pharmacokinetics of ganoderic acids a and f after oral administration of ling zhi preparation in healthy male volunteers.

Authors:  Supanimit Teekachunhatean; Sasinun Sadja; Chadarat Ampasavate; Natthakarn Chiranthanut; Noppamas Rojanasthien; Chaichan Sangdee
Journal:  Evid Based Complement Alternat Med       Date:  2012-04-22       Impact factor: 2.629
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