| Literature DB >> 10479334 |
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Abstract
Three novel isocoumarin (or isochromen) metabolites, dichlorodiaportin [3-(3, 3-dichloro-2-hydroxy-propyl)-8-hydroxy-6-methoxy-isochromen-1-one] (1), diaportinol [3-(2, 3-dihydroxy-propyl)-8-hydroxy-6-methoxy-isochromen-1-one] (2), and diaportinic acid [2-hydroxy-3-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)-propanoic acid] (3), were isolated from the cultures of Penicillium nalgiovense along with citreoisocoumarin (4) and 6-methyl-citreoisocoumarin (5). Their structures were elucidated by spectroscopic methods including UV, MS, and NMR.Entities:
Year: 1999 PMID: 10479334 DOI: 10.1021/np990066b
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050