Literature DB >> 10474673

Metronidazole ototoxicity--report of two cases.

S M Iqbal1, J G Murthy, P K Banerjee, K A Vishwanathan.   

Abstract

Two cases of bilateral moderate to severe sensorineural hearing loss due to oral administration of metronidazole are reported. There has been only one case report of deafness following metronidazole therapy in the world literature. The hearing loss recovered gradually in a period of four to six weeks following withdrawal of drug and oral steroid therapy. The possible mechanism of ototoxicity is discussed. Awareness by the treating physician of ototoxicity due to any drug is stressed.

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Year:  1999        PMID： 10474673     DOI： 10.1017/s0022215100143968

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN： 0022-2151            Impact factor:   1.469


  8 in total

1.  Metronidazole-induced central and peripheral nervous system toxicity.

Authors:  G Cação; S Fontes; M Salgado; T Rodrigues; Joana Damásio
Journal:  Neurol Sci       Date:  2015-05-20       Impact factor: 3.307

2.  Metronidazole-induced neurotoxicity presenting with sudden bilateral hearing loss, encephalopathy, and cerebellar dysfunction.

Authors:  Elmira Agah; Arman Habibi; Hamed Naderi; Abbas Tafakhori
Journal:  Eur J Clin Pharmacol       Date:  2016-10-15       Impact factor: 2.953

Review 3.  Metronidazole and tinnitus: A potential side effect?

Authors:  K L O'Donnell; D Barker
Journal:  Br Dent J       Date:  2016-03-25       Impact factor: 1.626

4.  Metronidazole-induced encephalopathy after prolonged metronidazole course for treatment of C. difficile colitis.

Authors:  Mark S Godfrey; Arkadiy Finn; Hadeel Zainah; Kwame Dapaah-Afriyie
Journal:  BMJ Case Rep       Date:  2015-01-16

Review 5.  Clinical and Neuroradiological Spectrum of Metronidazole Induced Encephalopathy: Our Experience and the Review of Literature.

Authors:  Ujjawal Roy; Ajay Panwar; Alak Pandit; Susanta Kumar Das; Bhushan Joshi
Journal:  J Clin Diagn Res       Date:  2016-06-01

6.  Sudden hearing loss subsequent to diarrhea: what is the missing link?

Authors:  Gholamali Jafari; Seyed Mohammadreza Hosseini; Shahin Akhondzadeh
Journal:  Daru       Date:  2014-01-08       Impact factor: 3.117

Review 7.  Ear Involvement in Inflammatory Bowel Disease: A Review of the Literature.

Authors:  Fotios S Fousekis; Maria Saridi; Eleni Albani; Fady Daniel; Konstantinos H Katsanos; Ioannis G Kastanioudakis; Dimitrios K Christodoulou
Journal:  J Clin Med Res       Date:  2018-06-27

8.  Metronidazole-induced encephalopathy in a patient with pyogenic spondylitis: a case report.

Authors:  Kazutaka Mizuta; Motoki Sonohata; Osamu Nozaki; Tomoki Kobatake; Daisuke Nakayama; Tadatsugu Morimoto; Masaaki Mawatari
Journal:  BMC Musculoskelet Disord       Date:  2018-09-18       Impact factor: 2.362
  8 in total

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