Literature DB >> 10474235

Nucleoside modifications affect the structure and stability of the anticodon of tRNA(Lys,3).

D R Davis1, P C Durant.   

Abstract

NMR spectroscopy was used to determine the solution structures of RNA oligonucleotides comprising the anticodon domain of tRNA(Lys,3). The structural effects of the pseudouridine modification at position 39 were investigated and are well correlated with changes in thermodynamic parameters. The loop conformation differs from that seen in tRNA(Phe) and provides an explanation of the critical role of modification in this tRNA.

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Year:  1999        PMID： 10474235     DOI： 10.1080/07328319908044790

Source DB:  PubMed          Journal:  Nucleosides Nucleotides        ISSN： 0732-8311


  4 in total

1.  A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.

Authors:  Sweta Vangaveti; William A Cantara; Jessica L Spears; Hasan DeMirci; Frank V Murphy; Sri V Ranganathan; Kathryn L Sarachan; Paul F Agris
Journal:  J Mol Biol       Date:  2020-01-14       Impact factor: 5.469

Review 2.  Wobble uridine modifications-a reason to live, a reason to die?!

Authors:  Raffael Schaffrath; Sebastian A Leidel
Journal:  RNA Biol       Date:  2017-02-23       Impact factor: 4.652

Review 3.  Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function.

Authors:  Ville Y P Väre; Emily R Eruysal; Amithi Narendran; Kathryn L Sarachan; Paul F Agris
Journal:  Biomolecules       Date:  2017-03-16

Review 4.  An integrated, structure- and energy-based view of the genetic code.

Authors:  Henri Grosjean; Eric Westhof
Journal:  Nucleic Acids Res       Date:  2016-07-22       Impact factor: 16.971
  4 in total

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