P Creidi1, P Humbert. 1. Department of Dermatology, Hôpital Saint-Jacques, Besançon, France.
Abstract
BACKGROUND: Retinaldehyde, the natural precursor of retinoic acid, should exert similar effects on photoaged skin. OBJECTIVE: To establish the efficacy and safety of topical retinaldehyde on photoaged skin. METHODS: Open and controlled clinical studies using image analysis of silicone skin replicas. RESULTS: Retinaldehyde proved efficient and safe. CONCLUSION: Retinaldehyde is efficient and well tolerated for the improvement of the signs of photoaging.
RCT Entities:
BACKGROUND:Retinaldehyde, the natural precursor of retinoic acid, should exert similar effects on photoaged skin. OBJECTIVE: To establish the efficacy and safety of topical retinaldehyde on photoaged skin. METHODS: Open and controlled clinical studies using image analysis of silicone skin replicas. RESULTS:Retinaldehyde proved efficient and safe. CONCLUSION:Retinaldehyde is efficient and well tolerated for the improvement of the signs of photoaging.