Literature DB >> 10473534

Hepatitis B virus DNA in blood samples positive for antibodies to core antigen and negative for surface antigen.

C Gutiérrez1, G León, C L Loureiro, N Uzcátegui, F Liprandi, F H Pujol.   

Abstract

Anti-hepatitis B core antigen (HBcAg)-positive hepatitis B surface antigen (HBsAg)-negative plasma samples from blood donors were tested by nested PCR. DNA positivity was more significantly associated with high levels of anti-HBcAg than with low levels of anti-HBsAg antibodies. Analysis of a dilution of anti-HBcAg antibodies might result in a more rational exclusion of anti-HBcAg-positive HBsAg-negative samples, reducing the number of donations discarded and enabling more countries to incorporate anti-HBcAg testing.

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Year:  1999        PMID： 10473534      PMCID： PMC95771          DOI： 10.1128/CDLI.6.5.768-770.1999

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  21 in total

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  5 in total

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