Literature DB >> 10469554

Receptor signaling: when dimerization is not enough.

G Jiang1, T Hunter.   

Abstract

Activation of receptors that signal via tyrosine kinase domains has been thought to involve receptor dimerization and transphosphorylation of juxtaposed catalytic domains. Recent results suggest things might be more complex - specific intersubunit conformational changes within a dimer can also be important.

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Substances：

Year:  1999        PMID： 10469554     DOI： 10.1016/s0960-9822(99)80357-1

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  47 in total

1.  TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor.

Authors:  J C Arevalo; B Conde; B L Hempstead; M V Chao; D Martin-Zanca; P Perez
Journal:  Mol Cell Biol       Date:  2000-08       Impact factor: 4.272

Review 2.  Self-incompatibility in the Brassicaceae: receptor-ligand signaling and cell-to-cell communication.

Authors:  Aardra Kachroo; Mikhail E Nasrallah; June B Nasrallah
Journal:  Plant Cell       Date:  2002       Impact factor: 11.277

3.  A putative molecular-activation switch in the transmembrane domain of erbB2.

Authors:  Sarel J Fleishman; Joseph Schlessinger; Nir Ben-Tal
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-02       Impact factor: 11.205

4.  Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz.

Authors:  A G Bang; C Kintner
Journal:  Genes Dev       Date:  2000-01-15       Impact factor: 11.361

5.  A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397.

Authors:  Qi Shi; David Boettiger
Journal:  Mol Biol Cell       Date:  2003-09-05       Impact factor: 4.138

Review 6.  New therapeutic strategies targeting transmembrane signal transduction in the immune system.

Authors:  Alexander B Sigalov
Journal:  Cell Adh Migr       Date:  2010-04-24       Impact factor: 3.405

7.  Insulin inhibits platelet-derived growth factor-induced cell proliferation.

Authors:  P Cirri; M L Taddei; P Chiarugi; F Buricchi; A Caselli; P Paoli; E Giannoni; G Camici; G Manao; G Raugei; G Ramponi
Journal:  Mol Biol Cell       Date:  2004-11-03       Impact factor: 4.138

Review 8.  Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.

Authors:  Edwin Li; Kalina Hristova
Journal:  Biochemistry       Date:  2006-05-23       Impact factor: 3.162

9.  Characterization of the SP11/SCR high-affinity binding site involved in self/nonself recognition in brassica self-incompatibility.

Authors:  Hiroko Shimosato; Naohiko Yokota; Hiroshi Shiba; Megumi Iwano; Tetsuyuki Entani; Fang-Sik Che; Masao Watanabe; Akira Isogai; Seiji Takayama
Journal:  Plant Cell       Date:  2007-01-12       Impact factor: 11.277

10.  Nerve growth factor signals via preexisting TrkA receptor oligomers.

Authors:  Paul S Mischel; Joy A Umbach; Sepehr Eskandari; Shane G Smith; Cameron B Gundersen; Guido A Zampighi
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033
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