Literature DB >> 10469089

Treatment of facial rhytids with a nonablative laser: a clinical and histologic study.

G M Menaker1, D A Wrone, R M Williams, R L Moy.   

Abstract

BACKGROUND: Current facial resurfacing modalities (laser, chemical peels, and dermabrasion) remove the epidermis and thus cause open wounds which carry significant risks and extended recovery periods. The nonablative laser is a novel Nd:YAG system designed to alleviate facial rhytids without injuring the epidermis. This new modality may offer patients rhytid removal without the risk seen in currently used resurfacing techniques.
OBJECTIVE: To describe a novel nonablative laser system and assess its safety profile and efficacy.
METHODS: Ten patients received laser treatments of their periocular rhytids and postauricular skin. Clinical variables (rhytid severity, hyperpigmentation, hypopigmentation, scarring, and level of discomfort) were assessed at 1 and 3 months posttreatment. Postauricular skin biopsies were taken both pre- and posttreatment for histologic analysis.
RESULTS: Patient discomfort was minimal. Three months posttreatment, 4 of 10 patients showed a one-point improvement in periocular rhytid severity when judged on a six-point scale. The results were not statistically significant. Biopsy analysis showed a small posttreatment increase in the amount of dermal collagen in three patients. A small decrease in collagen was noted in one patient. Three patients also showed a small posttreatment increase in the degree homogenization of dermal collagen. No change from baseline was noted in other assessed histologic parameters. Complications observed included hyperpigmentation in three patients and pitted scarring in three patients.
CONCLUSIONS: The nonablative laser gave clinically subtle and statistically insignificant improvement in rhytid severity. Unfortunately its use was associated with complications that included hyperpigmentation and scarring. This technology may eventually offer patients a new resurfacing option, but its efficacy and complication rate must be improved first.

Entities:  

Mesh:

Year:  1999        PMID: 10469089     DOI: 10.1046/j.1524-4725.1999.08158.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  10 in total

Review 1.  [Lasers and aesthetic dermatology].

Authors:  A J Stratigos; J S Dover; K A Arndt
Journal:  Hautarzt       Date:  2003-06-12       Impact factor: 0.751

2.  Effects of the 1,320-nm Nd:YAG laser on transepidermal water loss, histological changes, and collagen remodeling in skin.

Authors:  Yongyan Dang; Qiushi Ren; Huaxu Liu; Jingbo Ma; Jinsheng Zhang
Journal:  Lasers Med Sci       Date:  2006-07-29       Impact factor: 3.161

Review 3.  [Laser treatment of wrinkles. Update].

Authors:  Claudia Borelli
Journal:  Hautarzt       Date:  2007-03       Impact factor: 0.751

4.  The role of mast cells in non-ablative laser resurfacing with 1,320 nm neodymium:yttrium-aluminium-garnet laser.

Authors:  Yingbin Shang; Zhan Wang; Ying Pang; Peng Xi; Qiushi Ren
Journal:  Lasers Med Sci       Date:  2009-06-30       Impact factor: 3.161

5.  Fractional CO2 laser in the treatment of facial scars in children.

Authors:  Moshe Lapidoth; Shlomit Halachmi; Sarit Cohen; Dan Ben Amitai
Journal:  Lasers Med Sci       Date:  2013-03-26       Impact factor: 3.161

6.  Results of fractional ablative facial skin resurfacing with the erbium:yttrium-aluminium-garnet laser 1 week and 2 months after one single treatment in 30 patients.

Authors:  Mario A Trelles; Serge Mordon; Mariano Velez; Fernando Urdiales; Jean Luc Levy
Journal:  Lasers Med Sci       Date:  2008-02-19       Impact factor: 3.161

7.  Intense pulsed light, near infrared pulsed light, and fractional laser combination therapy for skin rejuvenation in Asian subjects: a prospective multi-center study in China.

Authors:  Li Tao; Jiaqiang Wu; Hui Qian; Zhong Lu; Yuanhong Li; Weizhen Wang; Xiaozhong Zhao; Ping Tu; Rui Yin; Leihong Xiang
Journal:  Lasers Med Sci       Date:  2015-08-13       Impact factor: 3.161

8.  Fractional microneedling radiofrequency and fractional 1927 nm thulium laser treatment offer synergistic skin rejuvenation: A pilot case series.

Authors:  Sooil Chun
Journal:  Laser Ther       Date:  2018-12-31

Review 9.  Facial rejuvenation and light: our personal experience.

Authors:  Mario A Trelles; Serge Mordon; R Glen Calderhead
Journal:  Lasers Med Sci       Date:  2006-11-23       Impact factor: 2.555

10.  Efficacy and Safety of Fractional CO2 Laser Resurfacing in Non-hypertrophic Traumatic and Burn Scars.

Authors:  Imran Majid; Saher Imran
Journal:  J Cutan Aesthet Surg       Date:  2015 Jul-Sep
  10 in total

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