Literature DB >> 10468849

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies.

J F Dimartino1, M L Cleary.   

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Year:  1999        PMID: 10468849     DOI: 10.1046/j.1365-2141.1999.01439.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


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  54 in total

1.  The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation.

Authors:  Marco Birke; Silke Schreiner; María-Paz García-Cuéllar; Kerstin Mahr; Fritz Titgemeyer; Robert K Slany
Journal:  Nucleic Acids Res       Date:  2002-02-15       Impact factor: 16.971

2.  MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function.

Authors:  Chi Wai So; Michael L Cleary
Journal:  Mol Cell Biol       Date:  2002-09       Impact factor: 4.272

3.  Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.

Authors:  Bernd B Zeisig; Tom Milne; María-Paz García-Cuéllar; Silke Schreiner; Mary-Ellen Martin; Uta Fuchs; Arndt Borkhardt; Sumit K Chanda; John Walker; Richard Soden; Jay L Hess; Robert K Slany
Journal:  Mol Cell Biol       Date:  2004-01       Impact factor: 4.272

4.  MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.

Authors:  Corina Buechele; Erin H Breese; Dominik Schneidawind; Chiou-Hong Lin; Johan Jeong; Jesus Duque-Afonso; Stephen H K Wong; Kevin S Smith; Robert S Negrin; Matthew Porteus; Michael L Cleary
Journal:  Blood       Date:  2015-08-26       Impact factor: 22.113

5.  Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.

Authors:  Dmitry Borkin; Szymon Klossowski; Jonathan Pollock; Hongzhi Miao; Brian M Linhares; Katarzyna Kempinska; Zhuang Jin; Trupta Purohit; Bo Wen; Miao He; Duxin Sun; Tomasz Cierpicki; Jolanta Grembecka
Journal:  J Med Chem       Date:  2018-05-23       Impact factor: 7.446

6.  The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.

Authors:  U Fuchs; G Rehkamp; O A Haas; R Slany; M Kōnig; S Bojesen; R M Bohle; C Damm-Welk; W D Ludwig; J Harbott; A Borkhardt
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205

7.  Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

Authors:  Zhong Wang; Kevin S Smith; Mark Murphy; Obdulio Piloto; Tim C P Somervaille; Michael L Cleary
Journal:  Nature       Date:  2008-09-17       Impact factor: 49.962

Review 8.  Molecular pathogenesis of MLL-associated leukemias.

Authors:  Mariko Eguchi; Minenori Eguchi-Ishimae; Mel Greaves
Journal:  Int J Hematol       Date:  2005-07       Impact factor: 2.490

9.  Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.

Authors:  Tomasz Cierpicki; Laurie E Risner; Jolanta Grembecka; Stephen M Lukasik; Relja Popovic; Monika Omonkowska; David D Shultis; Nancy J Zeleznik-Le; John H Bushweller
Journal:  Nat Struct Mol Biol       Date:  2009-12-13       Impact factor: 15.369

Review 10.  Regulating the leukaemia stem cell.

Authors:  Michael L Cleary
Journal:  Best Pract Res Clin Haematol       Date:  2009-12       Impact factor: 3.020

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