Literature DB >> 10468766

Is the measurement of serum testosterone routinely indicated in men with erectile dysfunction?

A K Fahmy1, S Mitra, A R Blacklock, K M Desai.   

Abstract

OBJECTIVE: To investigate the usefulness of serum testosterone levels as a relevant or useful indicator of sexual potency in men attending an erectile dysfunction clinic. PATIENTS AND METHODS: Ninety consecutive men attending the erectile dysfunction clinic completed a sexual-activity questionnaire, and underwent a focused physical examination and questioning about their medical history. The serum testosterone level was measured in all patients and the results analysed in relation to the patient's age. Patients with low serum testosterone levels commenced replacement therapy comprising three intramuscular injections of testosterone (Sustanontrade mark, Organon, The Netherlands) 250 mg every third week. Potency status and serum testosterone were reassessed after 3 months' treatment.
RESULTS: Of the 90 men, 28 (31%) were aged < 50 years whilst 62 (69%) were >/=50 years old. Nineteen (21%) patients overall had low testosterone levels; four of these were < 50 and 15 were >/=50 years old. Five of 90 patients had a decreased libido; two of these also had low testosterone levels and all were < 50 years old. Testosterone levels returned to normal in all patients who received replacement therapy but potency returned in only two (10%); both were in the older group.
CONCLUSION: Measuring testosterone was not helpful in assessing potency or libido and low serum levels were not related to age. Correcting low testosterone did not improve either impotence or libido.

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Year:  1999        PMID: 10468766     DOI: 10.1046/j.1464-410x.1999.00210.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  3 in total

Review 1.  Which patients with sexual dysfunction are suitable for testosterone replacement therapy?

Authors:  A Morelli; G Corona; S Filippi; S Ambrosini; G Forti; L Vignozzi; M Maggi
Journal:  J Endocrinol Invest       Date:  2007-11       Impact factor: 4.256

2.  Does regular consumption of green tea influence expression of vascular endothelial growth factor and its receptor in aged rat erectile tissue? Possible implications for vasculogenic erectile dysfunction progression.

Authors:  D Neves; M Assunção; F Marques; J P Andrade; H Almeida
Journal:  Age (Dordr)       Date:  2008-04-18

3.  A relationship of sex hormone levels and erectile dysfunction: which tests should be done routinely?

Authors:  Talha Müezzinoğu; Bilal Gümüş; Gökhan Temeltaş; Zeki Ari; Coşkun Büyüksu
Journal:  Yonsei Med J       Date:  2007-12-31       Impact factor: 2.759

  3 in total

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