[In Process Citation]

Endometriosis is a proliferative disease, which is often diagnosed with delay. Laparoscopy and histology are necessary for diagnosis. Different factors influence the success of therapy. Proliferative markers are very important for the differential diagnosis of active and inactive endometriosis. In a study it could be shown that endometriosis with high proliferative activity (high expression of Ki67) has a high response rate to GnRH-analogues treatment. Active endometriosis has to b distinguished to select an optimal treatment. A high proliferative activity of endometriosis should be treated with a hormonal-surgical combination.