| Literature DB >> 10466051 |
P Guillem1, V Billeret, M L Houcke, J P Triboulet.
Abstract
Post-operative chylothorax and chyloperitoneum resulting from a thoracic duct injury are possible complications of esophagectomy for carcinoma. Management of such conditions includes conservative methods (pleural drainage, chyle flow reduction and supportive nutrition) and surgery. Etilefrine, a sympathomimetic drug used in the management of postural hypotension, also causes smooth muscle contraction of the thoracic duct. We successfully treated three patients with post-esophagectomy chylothorax and chyloperitoneum using intravenous etilefrine. Etilefrine infusion allowed chyle flow resolution in a few days without any side-effects. As result of this experience, we believe that etilefrine deserves to be considered as an alternative therapy in the management of post-esophagectomy chylothorax/chyloperitoneum.Entities:
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Year: 1999 PMID： 10466051 DOI： 10.1046/j.1442-2050.1999.00021.x
Source DB: PubMed Journal: Dis Esophagus ISSN： 1120-8694 Impact factor: 3.429