| Literature DB >> 10465542 |
M Takahashi1, Y Ohgitani, A Ueno, H Mihara.
Abstract
We have designed and synthesized peptides derived from an anti-IgE antibody which has a potential for the treatment of allergy. It was indicated that conformational restriction of peptide via an intramolecular disulfide bond improved the binding affinity for IgE and that the peptide might have an ability to inhibit the IgE-receptor interaction.Entities:
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Year: 1999 PMID： 10465542 DOI： 10.1016/s0960-894x(99)00354-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823