Literature DB >> 10465536

Casein kinase II inhibitors isolated from two Brazilian plants Hymenaea parvifolia and Wulffia baccata.

M Ishibashi1, H Oda, M Mitamura, E Okuyama, K Komiyama, K Kawaguchi, T Watanabe, S de Mello Alves, T Maekawa, K Ohtsuki.   

Abstract

Two dihydroflavonol rhamnosides (1 and 2) isolated from the bark of Hymenaea parvifolia and two pentacyclic triterpenoids (3 and 6) obtained from the leaves of Wulffia baccata have been found to exhibit inhibitory effects of casein kinase II (CK-II) dose-dependently, suggesting that at higher doses more than 10 microM, these four compounds may act as potent CK-II suppressors of the CK-II-mediated activation of 60S acidic ribosomal P proteins in vitro.

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Year:  1999        PMID: 10465536     DOI: 10.1016/s0960-894x(99)00351-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Phytochemical and antibacterial investigations of the extracts and fractions from the stem bark of Hymenaea stigonocarpa Mart. ex Hayne and effect on ultrastructure of Staphylococcus aureus induced by hydroalcoholic extract.

Authors:  Gustavo Santiago Dimech; Luiz Alberto Lira Soares; Magda Assunção Ferreira; Anne Gabrielle Vasconcelos de Oliveira; Maria da Conceição Carvalho; Eulália Azevedo Ximenes
Journal:  ScientificWorldJournal       Date:  2013-12-14
  1 in total

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