Literature DB >> 104654

Genetic control of the immune response to the GAT terpolymer. I. Interstrain and interspecies cross-reactive idiotype.

J Thèze, J L Moreau.   

Abstract

An antiidiotypic antiserum specific for the GAT antibodies of BALB/c mice has been obtained in rabbits. This serum recognizes the GAT idiotype of 13 inbred strains of mice as well as the GAT idiotype present in sera of guinea-pigs, rats and rabbits immunized with GAT. Such an antiidiotypic antiserum should serve as a good reagent to detect putative idiotypic determinants on GAT-specific suppressor factor.

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Year:  1978        PMID： 104654

Source DB:  PubMed          Journal:  Ann Immunol (Paris)        ISSN： 0300-4910


  8 in total

1.  Structural bases for public idiotypic specificities of monoclonal antibodies directed against poly(Glu60Ala30Tyr10) and poly(Glu60Ala40) random copolymers.

Authors:  J Ruf; C Tonnelle; J Rocca-Serra; D Moinier; M Pierres; S T Ju; M E Dorf; J Thèze; M Fougereau
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

2.  Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response.

Authors:  C Schiff; M Milili; M Fougereau
Journal:  Nucleic Acids Res       Date:  1983-06-25       Impact factor: 16.971

3.  The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.

Authors:  P Ollier; J Rocca-Serra; G Sommé; J Thèze; M Fougereau
Journal:  EMBO J       Date:  1985-12-30       Impact factor: 11.598

4.  Recurrent idiotopes and internal images.

Authors:  N K Jerne; J Roland; P A Cazenave
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

5.  Genetic basis for expression of the idiotypic network. One unique Ig VH germline gene accounts for the major family of Ab1 and Ab3 (Ab1') antibodies of the GAT system.

Authors:  C Schiff; M Milili; I Hue; S Rudikoff; M Fougereau
Journal:  J Exp Med       Date:  1986-03-01       Impact factor: 14.307

6.  Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.

Authors:  J Rocca-Serra; H W Matthes; M Kaartinen; C Milstein; J Thèze; M Fougereau
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

7.  Interstrain conservation of the murine GAT-specific antibody V kappa repertoire as analyzed at the germline gene level.

Authors:  C Schiff; S Corbet; M Milili; M Fougereau
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

8.  V kappa gene family in (Glu60 Ala30 Tyr10)n (GAT)-specific antibodies that express CGAT (or pGAT) public idiotypic specificities. Protein and mRNA sequencing of eight monoclonal V kappa chains.

Authors:  C Tonnelle; J Rocca-Serra; A Moulin; D Moinier; M Fougereau
Journal:  J Exp Med       Date:  1983-11-01       Impact factor: 14.307
  8 in total

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