Literature DB >> 10465176

Altered lung antioxidant status in patients with mild asthma.

F J Kelly, I Mudway, A Blomberg, A Frew, T Sandström.   

Abstract

Lung lining fluid ascorbic acid (vitamin C) and alpha-tocopherol (vitamin E) concentrations are low in patients with mild asthma even though blood levels are normal or increased. These findings, along with the presence of increased amounts of oxidised glutathione in their airways, indicate that patients with asthma are subject to increased oxidative stress.

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Year:  1999        PMID: 10465176     DOI: 10.1016/S0140-6736(99)01812-7

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  69 in total

Review 1.  Isoforms of vitamin E differentially regulate inflammation.

Authors:  Joan M Cook-Mills; Christine A McCary
Journal:  Endocr Metab Immune Disord Drug Targets       Date:  2010-12       Impact factor: 2.895

2.  Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma.

Authors:  L G Wood; D A Fitzgerald; P G Gibson; D M Cooper; M L Garg
Journal:  Lipids       Date:  2000-09       Impact factor: 1.880

Review 3.  Oxidative stress in the pathogenesis of asthma.

Authors:  Russell P Bowler
Journal:  Curr Allergy Asthma Rep       Date:  2004-03       Impact factor: 4.806

4.  Oxidative stress: its role in air pollution and adverse health effects.

Authors:  Frank J Kelly
Journal:  Occup Environ Med       Date:  2003-08       Impact factor: 4.402

Review 5.  Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities.

Authors:  Anne M Fitzpatrick; Dean P Jones; Lou Ann S Brown
Journal:  Antioxid Redox Signal       Date:  2012-03-09       Impact factor: 8.401

6.  Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-kappaB and inflammatory responses in lung epithelial cells.

Authors:  B Ekstrand-Hammarström; C Osterlund; B Lilliehöök; A Bucht
Journal:  Clin Exp Immunol       Date:  2007-02       Impact factor: 4.330

7.  Alveolar macrophage cytokine response to air pollution particles: oxidant mechanisms.

Authors:  Amy Imrich; YaoYu Ning; Joy Lawrence; Brent Coull; Elena Gitin; Mitchell Knutson; Lester Kobzik
Journal:  Toxicol Appl Pharmacol       Date:  2006-12-15       Impact factor: 4.219

8.  Long term smoking with age builds up excessive oxidative stress in bronchoalveolar lavage fluid.

Authors:  K Nagai; T Betsuyaku; T Kondo; Y Nasuhara; M Nishimura
Journal:  Thorax       Date:  2006-03-14       Impact factor: 9.139

9.  Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity.

Authors:  Suzy A A Comhair; Weiling Xu; Sudakshina Ghosh; Frederik B J M Thunnissen; Alexandru Almasan; William J Calhoun; Allison J Janocha; Lemin Zheng; Stanley L Hazen; Serpil C Erzurum
Journal:  Am J Pathol       Date:  2005-03       Impact factor: 4.307

10.  Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment.

Authors:  Sergejs Berdnikovs; Hiam Abdala-Valencia; Christine McCary; Michelle Somand; Rokeisha Cole; Alex Garcia; Paul Bryce; Joan M Cook-Mills
Journal:  J Immunol       Date:  2009-04-01       Impact factor: 5.422

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